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SUCLA2 antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9P2R7 |
| Other Accession | NM_003850, NP_003841 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine, Yeast |
| Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine, Yeast |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 50317 Da |
| Gene ID | 8803 |
|---|---|
| Alias Symbol | A-BETA, SCS-betaA, MTDPS5 |
| Other Names | Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial, 6.2.1.5, ATP-specific succinyl-CoA synthetase subunit beta, Renal carcinoma antigen NY-REN-39, Succinyl-CoA synthetase beta-A chain, SCS-betaA, SUCLA2 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SUCLA2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SUCLA2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SUCLA2 {ECO:0000255|HAMAP-Rule:MF_03220, ECO:0000303|PubMed:34492704} |
|---|---|
| Function | ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA (PubMed:15877282, PubMed:34492704, PubMed:40108300). The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (By similarity). Also able to act as an ATP-specific itaconyl- and malyl- CoA synthetase (PubMed:40108300). |
| Cellular Location | Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03220, ECO:0000269|PubMed:15877282, ECO:0000269|PubMed:17287286, ECO:0000269|PubMed:25944712} |
| Tissue Location | Widely expressed. Not expressed in liver and lung. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Furuyama K.,et al.J. Clin. Invest. 105:757-764(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Johnson J.D.,et al.J. Biol. Chem. 273:27580-27586(1998).
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