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PDE6G antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P18545 |
| Other Accession | NM_002602, NP_002593 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 9643 Da |
| Gene ID | 5148 |
|---|---|
| Alias Symbol | DKFZp686C0587, MGC125749, PDEG |
| Other Names | Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma, 3.1.4.35, PDE6G, PDEG |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PDE6G antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | PDE6G antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PDE6G (HGNC:8789) |
|---|---|
| Synonyms | PDEG |
| Function | Inhibitory gamma subunit of the rod-specific cGMP phosphodiesterase (PDE6) complex, which hydrolyzes 3',5'-cyclic GMP in the phototransduction cascade. The PDE6 holoenzyme consists of two catalytic subunits (PDE6A and PDE6B) and two inhibitory gamma subunits. Light-activated GNAT1 relieves gamma subunit-mediated inhibition, enabling the catalytic subunits to hydrolyze cGMP and thereby mediate visual signal transduction and amplification. |
| Cellular Location | Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:P04972} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Tuteja N.,et al.Gene 88:227-232(1990).
Piriyev N.I.,et al.Dokl. Akad. Nauk SSSR 315:229-231(1990).
Hahn L.B.,et al.Invest. Ophthalmol. Vis. Sci. 35:1077-1082(1994).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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