GPLD1 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application
| WB |
|---|---|
| Primary Accession | P80108 |
| Other Accession | NM_001503, NP_001494 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 92336 Da |
| Gene ID | 2822 |
|---|---|
| Alias Symbol | GPIPLD, GPIPLDM, MGC22590, PIGPLD, PIGPLD1 |
| Other Names | Phosphatidylinositol-glycan-specific phospholipase D, PI-G PLD, 3.1.4.50, Glycoprotein phospholipase D, Glycosyl-phosphatidylinositol-specific phospholipase D, GPI-PLD, GPI-specific phospholipase D, GPLD1, PIGPLD1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-GPLD1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | GPLD1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GPLD1 (HGNC:4459) |
|---|---|
| Synonyms | PIGPLD1 |
| Function | Hydrolyzes the inositol phosphate linkage of glycosylphosphatidylinositol (GPI)-anchored membrane proteins, thereby releasing them from the cell surface. Cleaves on the inositol side of the anchor, leaving the phosphate group attached to the membrane (PubMed:17720976, PubMed:2760042). This release of GPI-anchored proteins can modulate diverse biological processes, including the activation of signaling pathways (PubMed:17720976). |
| Cellular Location | Secreted. Note=Associated with the High-Density Lipoproteins (HDL) {ECO:0000250|UniProtKB:P80109} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Tsang T.C.,et al.FASEB J. 6:A1922-A1922(1992).
Schofield J.N.,et al.Biochim. Biophys. Acta 1494:189-194(2000).
Tang J.H.,et al.Hunan Yi Ke Da Xue Xue Bao 26:96-97(2001).
Mungall A.J.,et al.Nature 425:805-811(2003).
Hoener M.C.,et al.Eur. J. Biochem. 206:747-757(1992).
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