癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Spaca3 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9D9X8 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Goat, Dog, Horse, Bovine, Sheep |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Goat, Dog, Horse, Bovine, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 25020 Da |
| Gene ID | 75622 |
|---|---|
| Other Names | Sperm acrosome membrane-associated protein 3, Lysozyme-like protein 3, Sperm lysozyme-like protein 1, mSLLP1, Sperm acrosome membrane-associated protein 3, membrane form, Sperm acrosome membrane-associated protein 3, processed form, Spaca3, Lyc3, Lyzl3, Sllp1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Spaca3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Spaca3 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Spaca3 |
|---|---|
| Synonyms | Lyc3, Lyzl3, Sllp1 |
| Function | Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N- acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro (By similarity). |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein. Note=Anterior acrosome in non- capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction |
| Tissue Location | The processed form is expressed in sperm (at protein level). Expressed strongly in testis and epididymis and weakly in pancreas. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Zhang K.,et al.Biol. Reprod. 73:1064-1071(2005).
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Herrero M.B.,et al.Dev. Biol. 284:126-142(2005).
Sachdev M.,et al.Dev. Biol. 363:40-51(2012).
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