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>   首页   >   产品   >   一抗   >   心血管   >   Anti-SKAP1 / SCAP1 Antibody    

Anti-SKAP1 / SCAP1 Antibody

Rabbit Anti Human Polyclonal Antibody

     
  • 14 - Anti-SKAP1 / SCAP1 Antibody  ALS17280
    Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession Q86WV1
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 41432 Da
Additional Information
Gene ID 8631
Alias Symbol SKAP1
Other Names SKAP1, Pp55, SKAP55, SKAP-55, SCAP1
Target/Specificity Human SKAP1 / SCAP1
Reconstitution & Storage PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsAnti-SKAP1 / SCAP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SKAP1
Synonyms SCAP1, SKAP55
Function Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T- cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.
Cellular Location Cytoplasm. Nucleus. Cell membrane. Note=Upon T- cell stimulation, translocates to lipid rafts at the cell membrane
Tissue Location Highly expressed in thymocytes and peripheral blood lymphocytes. Also expressed in spleen cells and testis. Present in T- cells (at protein level).
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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