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>   首页   >   产品   >   一抗   >   心血管   >   Anti-APOA1 / Apolipoprotein A 1 Antibody    

Anti-APOA1 / Apolipoprotein A 1 Antibody

Mouse Anti Human Monoclonal Antibody

     
  • 14 - Anti-APOA1 / Apolipoprotein A 1 Antibody  ALS17317
    Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • 14 - Anti-APOA1 / Apolipoprotein A 1 Antibody  ALS17317
    Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P
Primary Accession P02647
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Calculated MW 30778 Da
Concentration (mg/ml) 16.5 mg/ml
Additional Information
Gene ID 335
Alias Symbol APOA1
Other Names APOA1, ApoA-I, APOAI, Apolipoprotein A-I, Apolipoprotein A1, Apo-AI
Target/Specificity Specific for ApoA1, No cross reaction to Apo AII or Apo B
Reconstitution & Storage 15mM Potassium Phosphate, 0.85% Sodium Chloride, pH 7.5, 0.1% NaN3 Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsAnti-APOA1 / Apolipoprotein A 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name APOA1 (HGNC:600)
Function Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
Cellular Location Secreted.
Tissue Location Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease
Research Areas
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