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>   首页   >   产品   >   一抗   >   心血管   >   Anti-GJA1 / CX43 / Connexin 43 Antibody (C-Terminus)    

Anti-GJA1 / CX43 / Connexin 43 Antibody (C-Terminus)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IF, ICC
Primary Accession P17302
Predicted Human, Mouse, Rat, Rabbit, Chicken, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 43008 Da
Concentration (mg/ml) 1 mg/ml
Additional Information
Gene ID 2697
Alias Symbol GJA1
Other Names GJA1, Connexin-43, DFNB38, Connexin 43, Gap junction alpha-1 protein, GJAL, HSS, Gap junction protein alpha 1, ODDD, ODD, AVSD3, CX43, HLHS1, ODOD, SDTY3
Target/Specificity Recognizes endogenous levels of Connexin 43 protein.
Reconstitution & Storage PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsAnti-GJA1 / CX43 / Connexin 43 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GJA1
Synonyms GJAL
Function Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum {ECO:0000250|UniProtKB:P23242}. Note=Localizes at the intercalated disk (ICD) in cardiomyocytes and the proper localization at ICD is dependent on TMEM65. {ECO:0000250|UniProtKB:P23242}
Tissue Location Expressed at intercalated disks in the heart (at protein level) (PubMed:11741837, PubMed:18662195). Expressed in the fetal cochlea (PubMed:11741837).
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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