Anti-BOB / GPR15 Antibody (C-Terminus)
Rabbit Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application ![]()
| IHC-P, E |
---|---|
Primary Accession | P49685 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 40787 Da |
Concentration (mg/ml) | 1 mg/ml |
Gene ID | 2838 |
---|---|
Alias Symbol | GPR15 |
Other Names | GPR15, Brother of Bonzo, G protein-coupled receptor 15, G-protein coupled receptor 15, BOB, Gpr-15 |
Target/Specificity | Human GPR15. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-BOB / GPR15 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GPR15 |
---|---|
Function | G protein-coupled receptor that plays an important role in immune homeostasis (PubMed:33758080, PubMed:38918398). Acts via its natural ligand GPR15LG, a chemokine-like polypeptide strongly expressed in gastrointestinal tissues. GPR15-GPR15LG signaling axis regulates intestinal homeostasis and inflammation through the migration of immune cells (PubMed:33758080, PubMed:38918398). Controls thereby the specific homing of T-cells, particularly FOXP3+ regulatory T-cells (Tregs), to the large intestine lamina propria (By similarity). Also required for skin localization of thymus-derived dendritic epidermal T-cells (By similarity). Plays an important role in mediating cytoprotective function as well as angiogenesis of thrombomodulin (By similarity). Mechanistically, preferentially signals through the Gi/o pathway to inhibit adenylate cyclase activity and activate a phosphatidylinositol- calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores (PubMed:35510660). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Highly expressed in lymphoid tissues, including macrophages and peripheral blood mononuclear cells |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问,联系:0512-88856768 tech-china@abcepta.com.