癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-DUSP26 / MKP8 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| IHC-P |
|---|---|
| Primary Accession | Q9BV47 |
| Predicted | Human, Mouse, Hamster, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 23946 Da |
| Concentration (mg/ml) | 1 mg/ml |
| Gene ID | 78986 |
|---|---|
| Alias Symbol | DUSP26 |
| Other Names | DUSP26, DSP-4, NATA1, SKRP3, MAP kinase phosphatase 8, MKP-8, DUSP24, LDP-4, LDP4, MKP8 |
| Target/Specificity | Human DUSP26. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-DUSP26 / MKP8 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DUSP26 |
|---|---|
| Synonyms | DUSP24, LDP4, MKP8, NATA1, SKRP3 |
| Function | Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). |
| Cellular Location | Cytoplasm. Nucleus. Golgi apparatus. |
| Tissue Location | Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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