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>   首页   >   产品   >   一抗   >   心血管   >   Anti-BAFF Antibody (aa83-285, clone Buffy-1)   

Anti-BAFF Antibody (aa83-285, clone Buffy-1)

Rat Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, ICC, FC
Primary Accession Q9Y275
Predicted Human
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names Buffy-1
Calculated MW 31223 Da
Concentration (mg/ml) 1 mg/ml
Additional Information
Gene ID 10673
Alias Symbol TNFSF13B
Other Names TNFSF13B, B-cell-activating factor, BAFF, ApoL related ligand TALL-1, B-lymphocyte stimulator, CD257, BLYS, Delta4 BAFF, Delta BAFF, TALL-1, TALL1, ZTNF4, THANK, B lymphocyte stimulator, CD257 antigen, TNFSF20
Target/Specificity Recognizes membrane-bound human BAFF. Detects endogenous protein by FC.
Reconstitution & Storage Gel filtration
PrecautionsAnti-BAFF Antibody (aa83-285, clone Buffy-1) is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name TNFSF13B
Synonyms BAFF, BLYS, TALL1, TNFSF20, ZTNF4
Function Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T- cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B- cells and the B-cell response.
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines
Research Areas
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