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>   首页   >   产品   >   一抗   >   心血管   >   Anti-BAFF Antibody (aa83-285, clone Buffy-1)   

Anti-BAFF Antibody (aa83-285, clone Buffy-1)

Rat Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, ICC, FC
Primary Accession Q9Y275
Predicted Human
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names Buffy-1
Calculated MW 31223 Da
Concentration (mg/ml) 1 mg/ml
Additional Information
Gene ID 10673
Alias Symbol TNFSF13B
Other Names TNFSF13B, B-cell-activating factor, BAFF, ApoL related ligand TALL-1, B-lymphocyte stimulator, CD257, BLYS, Delta4 BAFF, Delta BAFF, TALL-1, TALL1, ZTNF4, THANK, B lymphocyte stimulator, CD257 antigen, TNFSF20
Target/Specificity Recognizes membrane-bound human BAFF. Detects endogenous protein by FC.
Reconstitution & Storage Gel filtration
PrecautionsAnti-BAFF Antibody (aa83-285, clone Buffy-1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFSF13B
Synonyms BAFF, BLYS, TALL1, TNFSF20, ZTNF4
Function Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T- cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B- cells and the B-cell response.
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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