Anti-HMOX1 / HO-1 Antibody (clone 5F12-B10)

Mouse Anti Human Monoclonal Antibody

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, FC
Primary Accession	P09601
Predicted	Human, Mouse, Rat, Bovine, Dog
Host	Mouse
Clonality	Monoclonal
Isotype	IgG1
Clone Names	5F12-B10
Calculated MW	32819 Da
Concentration (mg/ml)	1 mg/ml

Additional Information
Gene ID	3162
Alias Symbol	HMOX1
Other Names	HMOX1, BK286B10, HO-1, HSP32, Heat shock protein, 32-kD, Heme oxygenase (decycling) 1, Heme oxygenase 1, HO1
Reconstitution & Storage	Protein G purified
Precautions	Anti-HMOX1 / HO-1 Antibody (clone 5F12-B10) is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	HMOX1
Synonyms	HO, HO1
Function	[Heme oxygenase 1]: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron (PubMed:11121422, PubMed:19556236, PubMed:7703255). Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis (PubMed:20055707).
Cellular Location	Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side
Tissue Location	Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level)