癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-CES2 / Esterase Antibody (clone 4F12)
Mouse Anti Human Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC-P, E, IP |
|---|---|
| Primary Accession | O00748 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b,k |
| Clone Names | 4F12 |
| Calculated MW | 61807 Da |
| Concentration (mg/ml) | 0.5 mg/ml |
| Gene ID | 8824 |
|---|---|
| Alias Symbol | CES2 |
| Other Names | CES2, Carboxylesterase 2, CE-2, CES2A1, Cocaine esterase, Esterase, ICE, HCE-2, PCE-2 |
| Target/Specificity | Human CES2 |
| Reconstitution & Storage | Protein A purified |
| Precautions | Anti-CES2 / Esterase Antibody (clone 4F12) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CES2 (HGNC:1864) |
|---|---|
| Synonyms | ICE |
| Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed:9169443). Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine (PubMed:9169443). Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol (PubMed:28677105). Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2- arachidonoylglycerol and prostaglandins (PubMed:21049984). |
| Cellular Location | Endoplasmic reticulum lumen |
| Tissue Location | Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS17699
Size:
50 µg
Price:
¥ 4,787.00
替代产品:
