Anti-SLMAP / SLAP Antibody (clone 2A7)

Mouse Anti Human Monoclonal Antibody

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, E
Primary Accession	Q14BN4
Predicted	Human
Host	Mouse
Clonality	Monoclonal
Isotype	IgG2a,k
Clone Names	2A7
Calculated MW	95198 Da

Additional Information
Gene ID	7871
Alias Symbol	SLMAP
Other Names	SLMAP, KIAA1601, Sarcolemma associated protein, SLAP, Sarcolemmal-associated protein
Reconstitution & Storage	Protein A purified
Precautions	Anti-SLMAP / SLAP Antibody (clone 2A7) is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	SLMAP (HGNC:16643)
Synonyms	KIAA1601, SLAP
Function	Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex (PubMed:29063833, PubMed:30622739). The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth (PubMed:29063833, PubMed:30622739). May play a role during myoblast fusion (By similarity).
Cellular Location	Cell membrane, sarcolemma {ECO:0000250\|UniProtKB:P0C219}; Single-pass type IV membrane protein {ECO:0000250\|UniProtKB:P0C219}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250\|UniProtKB:Q3URD3}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250\|UniProtKB:Q3URD3}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250\|UniProtKB:Q3URD3} Note=Membrane-associated. Distributed in the transverse tubules and near the junctional sarcoplasmic reticulum (By similarity). Detected along the Z- and M-lines in cardiomyocytes (By similarity) {ECO:0000250\|UniProtKB:P0C219, ECO:0000250\|UniProtKB:Q3URD3} [Isoform 2]: Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Mitochondrion membrane; Single-pass type IV membrane protein [Isoform 4]: Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Mitochondrion membrane; Single-pass type IV membrane protein