癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-MFGE8 /Lactadherin Antibody (clone EDM45)
Mouse Anti Human Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IF, IP |
|---|---|
| Primary Accession | Q08431 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1,k |
| Clone Names | EDM45 |
| Calculated MW | 43105 Da |
| Gene ID | 4240 |
|---|---|
| Alias Symbol | MFGE8 |
| Other Names | MFGE8, Breast epithelial antigen BA46, EDIL1, HP47, Lactadherin, Medin, MFGM, Milk fat globule-EGF factor 8, HsT19888, OAcGD3S, SPAG10, Sperm associated antigen 10, MFG-E8, SED1, Sperm surface protein hP47, BA46, HMFG |
| Reconstitution & Storage | Protein G purified |
| Precautions | Anti-MFGE8 /Lactadherin Antibody (clone EDM45) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MFGE8 |
|---|---|
| Function | Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. |
| Cellular Location | Membrane; Peripheral membrane protein. Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:P79385}; Peripheral membrane protein {ECO:0000250|UniProtKB:P79385}. Note=Located in the acrosomal region of zona-pellucida bound sperm. {ECO:0000250|UniProtKB:P79385} |
| Tissue Location | Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS17800
