癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-DCXR Antibody (aa232-244)
Goat Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q7Z4W1 |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 25913 Da |
| Concentration (mg/ml) | 0.5 mg/ml |
| Gene ID | 51181 |
|---|---|
| Alias Symbol | DCXR |
| Other Names | DCXR, Carbonyl reductase 2, DCR, HCR2, HCRII, L-xylulose reductase, XR, Carbonyl reductase II, KIDCR, Kidney dicarbonyl reductase, p34H, SDR20C1, Sperm surface protein P34H |
| Target/Specificity | Human DCXR. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-DCXR Antibody (aa232-244) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | DCXR |
|---|---|
| Synonyms | SDR20C1 |
| Function | Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose (PubMed:11882650, PubMed:19337691, PubMed:40737316). Can use both NAD and NADP as cosubstrate but shows higher activity with NADP (PubMed:11882650). Participates in the uronate cycle of glucose metabolism (PubMed:11882650). May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules (PubMed:11882650). |
| Cellular Location | Apical cell membrane {ECO:0000250|UniProtKB:Q91X52}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q91X52}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q91XV4}. Note=Probably recruited to membranes via an interaction with phosphatidylinositol {ECO:0000250|UniProtKB:Q91XV4} |
| Tissue Location | Highly expressed in kidney, liver and epididymis (at protein level) (PubMed:11882650). In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region (PubMed:10385429). |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS17811
