癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-SOD1 / Cu-Zn SOD Antibody
Rabbit Anti Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC-P, E, IP |
|---|---|
| Primary Accession | P00441 |
| Predicted | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Sheep, Xenopus, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 15936 Da |
| Concentration (mg/ml) | 1 mg/ml |
| Gene ID | 6647 |
|---|---|
| Alias Symbol | SOD1 |
| Other Names | SOD1, ALS, ALS1, Cu/Zn superoxide dismutase, HSod1, Homodimer, IPOA, SOD, soluble, SOD, Superoxide dismutase [Cu-Zn], Superoxide dismutase 1, Indophenoloxidase A, Superoxide dismutase, cystolic |
| Target/Specificity | detects a 23 kDa proteinin human (and a 19 kDa protein in otherspecies) on SDS-PAGE immunoblots,corresponding to the molecular mass ofCu/Zn SOD. Positive control: HeLa cell lysate. |
| Reconstitution & Storage | Affinity purified |
| Precautions | Anti-SOD1 / Cu-Zn SOD Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SOD1 (HGNC:11179) |
|---|---|
| Function | Destroys radicals which are normally produced within the cells and which are toxic to biological systems (PubMed:18948262, PubMed:24140062). Catalyzes the oxidation of hydrogen sulfide (H2S) to sulfate, playing an important role in detoxifying H2S and limiting the accumulation of reactive sulfur species (RSS) such as persulfides and polysulfides (PubMed:36630448). |
| Cellular Location | Cytoplasm. Nucleus. Note=Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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