癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-MAP3K11 / MLK3 Antibody (clone 3D11)
Mouse Anti Human Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC-F, E |
|---|---|
| Primary Accession | Q16584 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a,k |
| Clone Names | 3D11 |
| Calculated MW | 92688 Da |
| Concentration (mg/ml) | 0.5 mg/ml |
| Gene ID | 4296 |
|---|---|
| Alias Symbol | MAP3K11 |
| Other Names | MAP3K11, Mixed lineage kinase 3, MLK3, Protein-tyrosine kinase PTK1, PTK1, SPRK, MLK-3, MEKK11 |
| Target/Specificity | Human MAP3K11 |
| Reconstitution & Storage | Protein A purified |
| Precautions | Anti-MAP3K11 / MLK3 Antibody (clone 3D11) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MAP3K11 (HGNC:6850) |
|---|---|
| Function | Activates the JUN N-terminal pathway. Required for serum- stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen- stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle. |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Location is cell cycle dependent |
| Tissue Location | Expressed in a wide variety of normal and neoplastic tissues including fetal lung, liver, heart and kidney, and adult lung, liver, heart, kidney, placenta, skeletal muscle, pancreas and brain. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS17851
Size:
50 µg
Price:
¥ 4,787.00
替代产品:
