癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-HRASLS2 Antibody (aa102-113)
Goat Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| IHC-P, E |
|---|---|
| Primary Accession | Q9NWW9 |
| Predicted | Human, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 17394 Da |
| Concentration (mg/ml) | 0.5 mg/ml |
| Gene ID | 54979 |
|---|---|
| Alias Symbol | HRASLS2 |
| Other Names | HRASLS2, HRAS-like suppressor 2, PLA1/2-2 |
| Target/Specificity | Human HRASLS2. This design was based on provisional sequence data. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-HRASLS2 Antibody (aa102-113) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLAAT2 (HGNC:17824) |
|---|---|
| Synonyms | HRASLS2 |
| Function | Exhibits both phospholipase A1/2 and acyltransferase activities (PubMed:19615464, PubMed:22605381, PubMed:22825852, PubMed:26503625). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (PubMed:19615464, PubMed:22605381, PubMed:22825852). For most substrates, PLA1 activity is much higher than PLA2 activity (PubMed:19615464). Shows O- acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (PubMed:19615464). Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N- acylphosphatidylethanolamine (NAPE), which serves as precursor for N- acylethanolamines (NAEs) (PubMed:19615464, PubMed:22605381, PubMed:22825852). Catalyzes N-acylation of PE using both sn-1 and sn-2 palmitoyl groups of PC as acyl donor (PubMed:22605381). Exhibits high phospholipase A1/2 activity and low N-acyltransferase activity (PubMed:22825852). |
| Cellular Location | Cytoplasm. Membrane; Single-pass membrane protein Note=Exhibits a granular pattern in the cytoplasm with preferential perinuclear localization. |
| Tissue Location | Expressed in liver, kidney, small intestine testis and colon (PubMed:19615464). Undetectable in testis, placenta, salivary gland and fetal brain (PubMed:18163183). |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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