癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-HMHA1 Antibody (aa57-71)
Goat Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| IHC-P, E |
|---|---|
| Primary Accession | Q92619 |
| Predicted | Human, Hamster, Monkey, Bovine, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 124614 Da |
| Concentration (mg/ml) | 0.5 mg/ml |
| Gene ID | 23526 |
|---|---|
| Alias Symbol | HMHA1 |
| Other Names | HMHA1, ARHGAP45, HLA-HA1, Ha-1, KIAA0223, HA1 |
| Target/Specificity | Human HMHA1 / HA-1. To avoid confusion please note that this antibody is designed to recognise the whole protein as coded by NP_036424.2 and will not recognise the peptide found eluted from HLA-A*0201 molecules by den Haan et al (Science. 1998 Feb 13 ... |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-HMHA1 Antibody (aa57-71) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ARHGAP45 (HGNC:17102) |
|---|---|
| Function | Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR- domin which is able to play an autoinhibitory effect on this RhoGAP activity. |
| Cellular Location | Cytoplasm. Cell projection, ruffle membrane |
| Tissue Location | Expressed on cells of the hematopoietic lineage. Detected in dendritic cells and epidermal Langerhans cells. Expressed in peripheral blood mononuclear cells, in all leukemia/lymphoma cell lines. Detected also in some solid tumors and tissues such as cancerous and non-cancerous tissue. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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