癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-FLJ22028 Antibody (aa24-37)
Goat Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q8WU10 |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 55793 Da |
| Concentration (mg/ml) | 0.5 mg/ml |
| Gene ID | 79912 |
|---|---|
| Alias Symbol | PYROXD1 |
| Other Names | PYROXD1, FLJ22028 |
| Target/Specificity | Human FLJ22028 |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-FLJ22028 Antibody (aa24-37) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PYROXD1 (HGNC:26162) |
|---|---|
| Function | Flavoprotein whose role is to protect RTCB, the catalytic subunit of the tRNA ligase complex (tRNA-LC) involved in tRNA splicing and unfolded protein response, from oxidative inactivation (PubMed:33930333). It directly binds and shields the catalytic center of RTCB, prior to guanylylation, when it is inactive and its active site is vulnerable to oxidation under aerobic conditions. The interaction of PYROXD1 with RTCB is allosterically regulated by NAD(P)H binding and reduction of its FAD cofactor, while reoxidation of PYROXD1 thanks to its NADPH dehydrogenase activity triggers the timed release of RTCB, enabling its subsequent activation. Thereby, this protective mechanism may also function as a molecular timer, regulating RTCB activation through controlled release (PubMed:40069351). |
| Cellular Location | Nucleus. Cytoplasm, cytosol. Cytoplasm, myofibril, sarcomere |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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