Anti-PNP / Nucleoside Phosphorylase Antibody (aa142-153)

Goat Anti Human Polyclonal Antibody

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, E
Primary Accession	P00491
Predicted	Human
Host	Goat
Clonality	Polyclonal
Calculated MW	32118 Da
Concentration (mg/ml)	0.5 mg/ml

Additional Information
Gene ID	4860
Alias Symbol	PNP
Other Names	PNP, Inosine phosphorylase, NP, Nucleoside phosphorylase, PUNP, PRO1837
Target/Specificity	Human Nucleoside Phosphorylase / PNP
Reconstitution & Storage	Immunoaffinity purified
Precautions	Anti-PNP / Nucleoside Phosphorylase Antibody (aa142-153) is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	PNP
Synonyms	NP
Function	Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (PubMed:23438750, PubMed:3029074, PubMed:9305964). Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine (PubMed:9305964).
Cellular Location	Cytoplasm, cytosol
Tissue Location	Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.