癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-CARD14 Antibody (aa291-340)
Rabbit Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| IHC-P, IF, E |
|---|---|
| Primary Accession | Q9BXL6 |
| Predicted | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 113270 Da |
| Gene ID | 79092 |
|---|---|
| Alias Symbol | CARD14 |
| Other Names | CARD14, BIMP2, Card-maguk protein 2, Carma 2, PrP, PSORS2, PSS1, CARMA2 |
| Target/Specificity | CAR14 Antibody detects endogenous levels of total CAR14 protein. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-CARD14 Antibody (aa291-340) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CARD14 |
|---|---|
| Synonyms | CARMA2 |
| Function | Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases (PubMed:11278692, PubMed:21302310, PubMed:27071417, PubMed:27113748). May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. |
| Cellular Location | [Isoform 1]: Cytoplasm [Isoform 3]: Cytoplasm |
| Tissue Location | Isoform 1 is detected in placenta and epidermal keratinocytes (PubMed:22521418). Isoform 2 is detected in leukocytes and fetal brain (PubMed:22521418). |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS17962
Size:
100 µl
Price:
¥ 4,923.00
替代产品:
