癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-KRAS Antibody
Rabbit Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P01116 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 21656 Da |
| Gene ID | 3845 |
|---|---|
| Alias Symbol | KRAS |
| Other Names | KRAS, C-K-RAS, C-Ki-ras, C-Kirsten-ras protein, GTPase KRas, K-ras p21 protein, K-RAS2B, K-RAS2, KRAS2, NS, NS3, K-RAS4A, KRAS1, RASK2, Transforming protein p21, Oncogene KRAS2, K-Ras 2, K-RAS2A, K-RAS4B, KI-RAS, PR310 c-K-ras oncogene |
| Target/Specificity | Human KRAS |
| Reconstitution & Storage | Caprylic acid and ammonium sulfate precipitation |
| Precautions | Anti-KRAS Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | KRAS |
|---|---|
| Synonyms | KRAS2, RASK2 |
| Function | Signal transducer in the Ras-MAPK signaling pathway that regulates cell proliferation and survival (PubMed:22711838, PubMed:23698361). Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621, PubMed:39809765). Activates MAPK1/MAPK3 resulting in phosphorylation and ultimately degradation of GJA1 (By similarity). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306). Recognized by LZTR1 that mediates its ubiquitination by a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex (PubMed:40934300). |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side. Endomembrane system. Cytoplasm |
| Tissue Location | Expressed throughout the epidermis, but weakly expressed in the stratum corneum and dermis (at protein level) |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS17974
Size:
100 µg
Price:
¥ 5,331.00
替代产品:
