癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-HNRNPC / HNRNP C Antibody (clone 4F4)
Mouse Anti Human Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IF, E, IP |
|---|---|
| Primary Accession | P07910 |
| Predicted | Human, Hamster, Monkey, Chicken |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone Names | 4F4 |
| Calculated MW | 33670 Da |
| Concentration (mg/ml) | 1 mg/ml |
| Gene ID | 3183 |
|---|---|
| Alias Symbol | HNRNPC |
| Other Names | HNRNPC, HNRPC, HnRNP C1/C2, HNRNP |
| Target/Specificity | This antibody recognizes the two HNRNP C proteins of 41kD (C1) and 43kD (C2) in human cells, and the corresponding proteins in monkey, hamster and chicken. |
| Reconstitution & Storage | Protein A purified |
| Precautions | Anti-HNRNPC / HNRNP C Antibody (clone 4F4) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | HNRNPC |
|---|---|
| Synonyms | HNRPC |
| Function | Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621). May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671). |
| Cellular Location | Nucleus. Note=Component of ribonucleosomes |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS18004
Size:
50 µl
Price:
¥ 4,380.00
替代产品:
