Anti-PRDX3 / Peroxiredoxin 3 Antibody (aa44-93)

Rabbit Anti Human Polyclonal Antibody

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, E
Primary Accession	P30048
Predicted	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Calculated MW	27693 Da

Additional Information
Gene ID	10935
Alias Symbol	PRDX3
Other Names	PRDX3, Antioxidant protein 1, AOP1, AOP-1, HBC189, Peroxiredoxin III, PRO1748, Peroxiredoxin-3, Prx-III, SP-22, Peroxiredoxin 3, Protein MER5 homolog
Target/Specificity	PRX III antibody detects endogenous levels of PRX III.
Reconstitution & Storage	Immunoaffinity purified
Precautions	Anti-PRDX3 / Peroxiredoxin 3 Antibody (aa44-93) is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	PRDX3
Synonyms	AOP1
Function	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (PubMed:17707404, PubMed:29438714, PubMed:33889951, PubMed:7733872). Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (PubMed:12492477). Required for the maintenance of physical strength (By similarity).
Cellular Location	Mitochondrion. Cytoplasm. Early endosome. Note=Localizes to early endosomes in a RPS6KC1-dependent manner.