癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-NPPB / BNP Antibody (clone 2D11)
Mouse Anti Human Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC-P, E, IP |
|---|---|
| Primary Accession | P16860 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG3,k |
| Clone Names | 2D11 |
| Calculated MW | 14726 Da |
| Concentration (mg/ml) | 0.3 mg/ml |
| Gene ID | 4879 |
|---|---|
| Alias Symbol | NPPB |
| Other Names | NPPB, BNP, Natriuretic peptides B, Natriuretic peptide B, Natriuretic protein, Brain type natriuretic peptide |
| Target/Specificity | Human NPPB / BNP |
| Reconstitution & Storage | Protein A purified |
| Precautions | Anti-NPPB / BNP Antibody (clone 2D11) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | NPPB |
|---|---|
| Function | [Brain natriuretic peptide 32]: Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (PubMed:1672777, PubMed:17372040, PubMed:1914098, PubMed:9458824). May also function as a paracrine antifibrotic factor in the heart (By similarity). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses (PubMed:1672777, PubMed:17349887, PubMed:17372040, PubMed:21098034, PubMed:25339504, PubMed:9458824). Involved in regulating the extracellular fluid volume and maintaining the fluid- electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion (PubMed:1914098, PubMed:9458824). Binds the clearance receptor NPR3 (PubMed:16870210). |
| Cellular Location | [NT-proBNP]: Secreted Note=Detected in blood. [Brain natriuretic peptide 32]: Secreted. Note=Detected in blood. |
| Tissue Location | [Brain natriuretic peptide 32]: Detected in the cardiac atria (at protein level) (PubMed:2136732, PubMed:2138890) Detected in the kidney distal tubular cells (at protein level) (PubMed:9794555). |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS18181
Size:
50 µg
Price:
¥ 4,787.00
替代产品:
