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>   首页   >   产品   >   一抗   >   心血管   >   Anti-ISGF3 / IRF9 Antibody   

Anti-ISGF3 / IRF9 Antibody

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IF, IP
Primary Accession Q00978
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 43696 Da
Additional Information
Gene ID 10379
Alias Symbol IRF9
Other Names IRF9, Interferon regulatory factor 9, ISGF3 p48 subunit, ISGF3G, p48, IRF-9, ISGF3, ISGF-3 gamma
Target/Specificity Human ISGF3 / IRF9
Reconstitution & Storage Affinity purified
PrecautionsAnti-ISGF3 / IRF9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name IRF9
Synonyms ISGF3G
Function Transcription factor that plays an essential role in anti- viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Cellular Location Cytoplasm. Nucleus Note=Translocated into the nucleus upon activation by IFN-alpha/beta
Research Areas
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