Anti-LIPC / Hepatic Lipase Antibody (aa301-350)

Rabbit Anti Human Polyclonal Antibody

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, E
Primary Accession	P11150
Predicted	Human
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Calculated MW	55914 Da

Additional Information
Gene ID	3990
Alias Symbol	LIPC
Other Names	LIPC, Hepatic lipase, HL, HDLCQ12, Hepatic triglyceride lipase, Lipase member C, HTGL, Lipase, hepatic, Triacylglycerol lipase hepatic, Hepatic triacylglycerol lipase
Target/Specificity	LIPC Antibody detects endogenous levels of LIPC.
Reconstitution & Storage	Immunoaffinity purified
Precautions	Anti-LIPC / Hepatic Lipase Antibody (aa301-350) is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	LIPC
Synonyms	HTGL
Function	Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles (PubMed:12032167, PubMed:26193433, PubMed:7592706, PubMed:8798474). Also exhibits lysophospholipase activity (By similarity). Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates (By similarity). In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position (PubMed:26193433).
Cellular Location	Secreted.