癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-CR1 / CD35 Antibody (clone C35.1)
Mouse Anti Human Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| IHC-P |
|---|---|
| Primary Accession | P17927 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1,k |
| Clone Names | C35.1 |
| Calculated MW | 223663 Da |
| Concentration (mg/ml) | 0.2 mg/ml |
| Gene ID | 1378 |
|---|---|
| Alias Symbol | CR1 |
| Other Names | CR1, C3b/C4b receptor, C3-binding protein, CD35, C3BR, Knops blood group antigen, C4BR, CD35 antigen, Complement receptor type 1, KN |
| Target/Specificity | Human CR1 / CD35 |
| Reconstitution & Storage | Purified |
| Precautions | Anti-CR1 / CD35 Antibody (clone C35.1) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CR1 |
|---|---|
| Synonyms | C3BR |
| Function | Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages (PubMed:2963069). Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation (PubMed:2963069). Also acts in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d (PubMed:2972794, PubMed:8175757). Also plays a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells (PubMed:25742728). |
| Cellular Location | Membrane; Single- pass type I membrane protein |
| Tissue Location | Present on erythrocytes, a subset of T cells, mature B cells, follicular dendritic cells, monocytes and granulocytes |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS18390
Size:
250 µl
Price:
¥ 4,380.00
替代产品:
