癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-MDM4 / MDMX Antibody (clone 4G3)
Mouse Anti Human Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | O15151 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Clone Names | 4G3 |
| Calculated MW | 54864 Da |
| Concentration (mg/ml) | 1 mg/ml |
| Gene ID | 4194 |
|---|---|
| Alias Symbol | MDM4 |
| Other Names | MDM4, Mdm2-like p53-binding protein, MDMX, HDMX, MRP1, p53-binding protein Mdm4, Protein Mdm4, Double minute 4 protein, MDM4-related protein 1, Protein Mdmx |
| Target/Specificity | Human MDM4 / MDMX |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-MDM4 / MDMX Antibody (clone 4G3) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MDM4 |
|---|---|
| Synonyms | MDMX |
| Function | Contributes to p53/TP53 regulation (PubMed:32300648). Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding their transcriptional activation domains. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. |
| Cellular Location | Nucleus. Cytoplasm |
| Tissue Location | Expressed in all tissues tested with high levels in thymus |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ALS18427
Size:
50 µl
Price:
¥ 4,380.00
替代产品:
