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>   首页   >   产品   >   一抗   >   心血管   >   Anti-FLG / Filaggrin Antibody (N-Terminus)   

Anti-FLG / Filaggrin Antibody (N-Terminus)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P
Primary Accession P20930
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 435170 Da
Concentration (mg/ml) 1 mg/ml
Additional Information
Gene ID 2312
Alias Symbol FLG
Other Names FLG, ATOD2, Epidermal filaggrin, Filaggrin
Target/Specificity Recognizes endogenous levels of Filaggrin protein.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-FLG / Filaggrin Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name FLG
Function Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.
Cellular Location Cytoplasmic granule. Note=In the stratum granulosum of the epidermis, localized within keratohyalin granules (PubMed:1429717). In granular keratinocytes and in lower corneocytes, colocalizes with calpain-1/CAPN1 (PubMed:21531719).
Tissue Location Expressed in skin, thymus, stomach, tonsils, testis, placenta, kidney, pancreas, mammary gland, bladder, thyroid, salivary gland and trachea, but not detected in heart, brain, liver, lung, bone marrow, small intestine, spleen, prostate, colon, or adrenal gland (PubMed:19384417). In the skin, mainly expressed in stratum granulosum of the epidermis (PubMed:1429717, PubMed:19384417)
Research Areas
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