癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-LYPLA2 Antibody
Rabbit Anti Human Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| IHC-P, IF, E |
|---|---|
| Primary Accession | O95372 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 24737 Da |
| Concentration (mg/ml) | 1 mg/ml |
| Gene ID | 11313 |
|---|---|
| Alias Symbol | LYPLA2 |
| Other Names | LYPLA2, Acyl-protein thioesterase 2, APT-2, APT2, DJ886K2.4, LysoPLA II, LPL-II, Lysophospholipase II |
| Target/Specificity | Human LYPLA2 |
| Reconstitution & Storage | Caprylic acid and ammonium sulfate precipitation |
| Precautions | Anti-LYPLA2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | LYPLA2 |
|---|---|
| Synonyms | APT2 |
| Function | Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS (PubMed:21152083, PubMed:28826475). Deacylates GAP43 (PubMed:21152083). Mediates depalmitoylation of ZDHHC6 (PubMed:28826475). Has lysophospholipase activity (PubMed:25301951). Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha- glycerol ester (PGF2-alpha-G) (PubMed:25301951). Hydrolyzes 1- arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide (PubMed:25301951). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed in various breast cancer cell lines. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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