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>   首页   >   产品   >   一抗   >   心血管   >   Anti-DHAND / HAND2 Antibody   

Anti-DHAND / HAND2 Antibody

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IF
Primary Accession P61296
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 23666 Da
Additional Information
Gene ID 9464
Alias Symbol HAND2
Other Names HAND2, DHand, DHAND2, Hed, Thing2, BHLHa26
Target/Specificity Human DHAND / HAND2
Reconstitution & Storage Affinity purified
PrecautionsAnti-DHAND / HAND2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HAND2
Synonyms BHLHA26, DHAND
Function Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior- posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG- 3' (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Tissue Location Heart.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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