EIF4B Antibody (Ascites)
Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, E |
---|---|
Primary Accession | P23588 |
Other Accession | NP_001408.2 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Clone Names | 355CT12.6.5 |
Calculated MW | 69151 Da |
Gene ID | 1975 |
---|---|
Other Names | Eukaryotic translation initiation factor 4B, eIF-4B, EIF4B |
Target/Specificity | This EIF4B monoclonal antibody is generated from mouse immunized with EIF4B recombinant protein. |
Dilution | WB~~1:500~4000 E~~Use at an assay dependent concentration. |
Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | EIF4B Antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EIF4B |
---|---|
Function | Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
REFERENCES
Mokas, S., et al. Mol. Biol. Cell 20(11):2673-2683(2009)
Rozovsky, N., et al. RNA 14(10):2136-2148(2008)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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