癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
UBL5 Antibody(Ascites)
Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BZL1 |
| Other Accession | Q9EPV8, Q3T0Z3, NP_001041706.1, NP_077268.1 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone Names | 429CT16.3.1 |
| Calculated MW | 8547 Da |
| Gene ID | 59286 |
|---|---|
| Other Names | Ubiquitin-like protein 5, UBL5 |
| Target/Specificity | Purified His-tagged UBL5 protein(Fragment) was used to produced this monoclonal antibody. |
| Dilution | WB~~1:500~8000 E~~Use at an assay dependent concentration. |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UBL5 Antibody(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UBL5 |
|---|---|
| Function | Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins (PubMed:25092792). Participates thereby in pre- mRNA splicing by maintaining spliceosome integrity. Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers (PubMed:25862789). Also plays a protective role against ER stress-induced apoptosis (PubMed:37315790). |
| Cellular Location | Cytoplasm. Nucleus. Nucleus, Cajal body |
| Tissue Location | Ubiquitous. Highest level of expression in heart, skeletal muscle, kidney, liver, iris and lymphoblasts |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Ubiquitin-like proteins (UBLs) are thought to be reversible modulators of protein function rather than protein degraders like ubiquitin (MIM 191339).
REFERENCES
de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Sentinelli, F., et al. J. Pediatr. Endocrinol. Metab. 21(12):1139-1145(2008)
Bozaoglu, K., et al. Hum. Biol. 78(2):147-159(2006)
Wilkinson, C.R., et al. Curr. Biol. 14(24):2283-2288(2004)
Jowett, J.B., et al. Diabetes 53(9):2467-2472(2004)
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
