癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TPIPb Antibody (C-term)(Ascites) 精选
Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q6XPS3 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone Names | 978CT6.1.4 |
| Calculated MW | 61112 Da |
| Gene ID | 93492 |
|---|---|
| Other Names | Phosphatidylinositol 3, 5-trisphosphate 3-phosphatase TPTE2, Lipid phosphatase TPIP, TPTE and PTEN homologous inositol lipid phosphatase, TPTE2, TPIP |
| Target/Specificity | Purified His-tagged TPIPb protein was used to produced this monoclonal antibody. |
| Dilution | WB~~1:4000 E~~Use at an assay dependent concentration. |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TPIPb Antibody (C-term)(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TPTE2 |
|---|---|
| Synonyms | TPIP {ECO:0000303|PubMed:11716755} |
| Function | Acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate. |
| Cellular Location | [Isoform 3]: Endoplasmic reticulum membrane; Multi-pass membrane protein [Isoform 4]: Cytoplasm |
| Tissue Location | Isoform 3 is expressed in testis, brain and stomach while isoform 4 seems to be testis-specific |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Walker S.M., et al. Biochem. J. 360:277-283(2001).
Tapparel C., et al. Gene 323:189-199(2003).
Dunham A., et al. Nature 428:522-528(2004).
Mural R.J., et al. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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