AFP Antibody
Purified Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, IHC-P, E |
---|---|
Primary Accession | P02771 |
Reactivity | Human |
Host | Mouse |
Clonality | monoclonal |
Isotype | IgG2b,k |
Clone Names | 1087CT8.3.5 |
Calculated MW | 68678 Da |
Gene ID | 174 |
---|---|
Other Names | Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, AFP, HPAFP |
Target/Specificity | This AFP antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 281-609 amino acids from human AFP. |
Dilution | WB~~1:500 IHC-P~~1:100~500 E~~Use at an assay dependent concentration. |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | AFP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AFP |
---|---|
Synonyms | HPAFP |
Function | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
Cellular Location | Secreted. |
Tissue Location | Plasma. Synthesized by the fetal liver and yolk sac |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
REFERENCES
Morinaga T.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:4604-4608(1983).
Gibbs P.E.M.,et al.Biochemistry 26:1332-1343(1987).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Sakai M.,et al.J. Biol. Chem. 260:5055-5060(1985).
McVey J.H.,et al.Hum. Mol. Genet. 2:379-384(1993).

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