癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-CD75 (Transferrin receptor) Antibody
Our Anti-CD75 (Transferrin receptor) mouse monoclonal primary antibody from PhosphoSolutions is prod
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC |
|---|---|
| Primary Accession | P15907 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgM |
| Clone Names | LN1 |
| Calculated MW | 46605 Da |
| Gene ID | 6480 |
|---|---|
| Other Names | 6 sialyltransferase antibody, 6-sialyltransferase 1 antibody, 6-ST 1 antibody, Alpha 2 antibody, Alpha 2, 6 ST 1 antibody, Alpha 2, 6 ST antibody, B cell antigen CD75 antibody, B-cell antigen CD75 antibody, Beta galactoside alpha 2, 6 sialyltransferase 1 antibody, Beta-galactoside alpha-2 antibody, CMP N acetylneuraminate beta galactosamide alpha 2, 6 sialyltransferase 1 antibody, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2 antibody, MGC48859 antibody, Sialyltransferase 1 (beta galactoside alpha 2, 6 sialyltransferase) antibody, Sialyltransferase 1 antibody, SIAT1 antibody, SIAT1_HUMAN antibody, ST6 beta galactosamide alpha 2, 6 sialyltranferase 1 antibody, ST6Gal I antibody, ST6GAL1 antibody, ST6GalI antibody, ST6N antibody |
| Target/Specificity | CD75, also known as β-galactoside α2,6-sialyltransferase, is a specific carbohydrate antigen that is predominantly expressed on B cell lymphocytes. β-galactoside α2,6-sialyltransferase is an enzyme that catalyzes the addition of sialic acid to growing carbohydrate chains of glycoproteins (Guy, K., et al, 1991). CD75 is a major component of the lymphoid cell surface that serves as a ligand for cell adhesion molecules (Paulson, J.C., et al, 1989). The LN-1 clone reacts positively with red blood cell precursors of the bone marrow, ciliated epithelial cells of the bronchus, distal tubular cells of the kidney, and ductal cells from several organs including the breast and prostate (Epstein, A.L., et al, 1984). CD75 has been shown to be superior to other B cell markers in detecting lymphocyte predominant cells through their cytoplasmic and membraneous staining, especially in typical nodular lymphocyte-predominant Hodgkin lymphoma patterns (Carbone, A., et al, 2014). |
| Dilution | WB~~1:1000 IHC~~1:100~500 |
| Format | Protein L purified |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Anti-CD75 (Transferrin receptor) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Shipping | Blue Ice |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
CD75, also known as β-galactoside α2,6-sialyltransferase, is a specific carbohydrate antigen that is predominantly expressed on B cell lymphocytes. β-galactoside α2,6-sialyltransferase is an enzyme that catalyzes the addition of sialic acid to growing carbohydrate chains of glycoproteins (Guy, K., et al, 1991). CD75 is a major component of the lymphoid cell surface that serves as a ligand for cell adhesion molecules (Paulson, J.C., et al, 1989). The LN-1 clone reacts positively with red blood cell precursors of the bone marrow, ciliated epithelial cells of the bronchus, distal tubular cells of the kidney, and ductal cells from several organs including the breast and prostate (Epstein, A.L., et al, 1984). CD75 has been shown to be superior to other B cell markers in detecting lymphocyte predominant cells through their cytoplasmic and membraneous staining, especially in typical nodular lymphocyte-predominant Hodgkin lymphoma patterns (Carbone, A., et al, 2014).
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