癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-PEBP (phosphatidylethanolamie binding protein) Antibody
Our Anti-PEBP (phosphatidylethanolamie binding protein) primary antibody from PhosphoSolutions is ra
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | P31044 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 20801 Da |
| Gene ID | 29542 |
|---|---|
| Other Names | Epididymis luminal protein 210 antibody, Epididymis secretory protein Li 34 antibody, Epididymis secretory protein Li 96 antibody, HCNP antibody, HCNPpp antibody, HEL 210 antibody, HEL S 34 antibody, HEL S 96 antibody, Hippocampal cholinergic neurostimulating peptide antibody, Neuropolypeptide h3 antibody, PBP antibody, PEBP antibody, PEBP 1 antibody, PEBP-1 antibody, Pebp1 antibody, PEBP1_HUMAN antibody, Phosphatidylethanolamine binding protein antibody, Phosphatidylethanolamine binding protein 1 antibody, Prostatic binding protein antibody, Prostatic-binding protein antibody, R kip antibody, Raf kinase inhibitor protein antibody, Raf kinase inhibitory protein antibody, RKIP antibody |
| Target/Specificity | Phosphatidylethanolamine binding protein (PEBP), also known as Raf kinase inhibitory protein (RKIP) is a highly conserved multifunctional protein that modulates the Raf/MAPK signaling cascade and has been implicated as a suppressor of metastatic cancer (Trakul N et al., 2005). PEBP has been shown to not only inhibit cell proliferation but also to induce differentiation of human keratinocytes (Yamazaki et al., 2004). Dysregulation of calpain activity results in cellular degeneration in conditions such as Alzheimer’s disease and recently PEBP has been identified as a potential in vivo calpain substrate (Chen at al., 2006). |
| Dilution | WB~~1:1000 |
| Format | Neat Serum |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Anti-PEBP (phosphatidylethanolamie binding protein) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Shipping | Blue Ice |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Phosphatidylethanolamine binding protein (PEBP), also known as Raf kinase inhibitory protein (RKIP) is a highly conserved multifunctional protein that modulates the Raf/MAPK signaling cascade and has been implicated as a suppressor of metastatic cancer (Trakul N et al., 2005). PEBP has been shown to not only inhibit cell proliferation but also to induce differentiation of human keratinocytes (Yamazaki et al., 2004). Dysregulation of calpain activity results in cellular degeneration in conditions such as Alzheimer’s disease and recently PEBP has been identified as a potential in vivo calpain substrate (Chen at al., 2006).
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