癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Tubulin, beta III Antibody
Our Anti-Tubulin, beta III primary antibody from PhosphoSolutions is mouse monoclonal. It detects mo
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- 实验流程
- 背景知识
Application 
| WB, IHC, ICC |
|---|---|
| Primary Accession | Q4QRB4 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG |
| Clone Names | AA10 |
| Calculated MW | 50419 Da |
| Gene ID | 246118 |
|---|---|
| Other Names | beta 3 tubulin antibody, beta-4 antibody, beta III Tubulin, CDCBM antibody, CDCBM1 antibody, CFEOM3 antibody, CFEOM3A antibody, FEOM3 antibody, M(beta)3 antibody, M(beta)6 antibody, MC1R antibody, Neuron specific beta III Tubulin antibody, Neuron-specific class III beta-tubulin antibody, QccE-11995 antibody, QccE-15186 antibody, TBB3_HUMAN antibody, Tubb 3 antibody, TUBB3 antibody, TUBB4 antibody, Tubulin beta 3 antibody, Tubulin beta 3 chain antibody, Tubulin beta 4 antibody, Tubulin beta III antibody, Tubulin beta-3 chain antibody, Tubulin beta-4 chain antibody, Tubulin beta-III antibody |
| Target/Specificity | Tubulin is the major constituent of microtubules, existing as a heterodimer of the α and β subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003) |
| Dilution | WB~~1:1000 IHC~~1:100~500 ICC~~N/A |
| Format | Protein G Purified |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Anti-Tubulin, beta III Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Shipping | Blue Ice |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Tubulin is the major constituent of microtubules, existing as a heterodimer of the α and β subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)
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