癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FBLN2 Antibody
Purified Mouse Monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | P98095 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 7H4F6; 3B9A11 |
| Isotype | IgG1 |
| Calculated MW | 126573 Da |
| Description | FBLN2: fibulin 2. This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Immunogen | Purified recombinant fragment of FBLN2 (aa180-440) expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Gene ID | 2199 |
|---|---|
| Other Names | Fibulin-2, FIBL-2, FBLN2 |
| Dilution | WB~~1/500 - 1/2000 E~~N/A |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FBLN2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FBLN2 |
|---|---|
| Function | Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108). |
| Cellular Location | Secreted, extracellular space, extracellular matrix |
| Tissue Location | Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1. J Biol Chem. 1996 Aug 9;271(32):19489-96. 2. Eur J Hum Genet. 1996;4(5):292-5. 3. J Invest Dermatol. 1999 Jan;112(1):97-101. 4. Br J Dermatol. 2001 Aug;145(2):217-22.
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