SRC Antibody

Purified Mouse Monoclonal Antibody

Figure 1: Western blot analysis using SRC mouse mAb against truncated SRC-His recombinant protein (1) and PMA treated THP-1 cell lysate (2).

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, E
Primary Accession	P12931
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Clone Names	5D10C4
Isotype	IgG2a
Calculated MW	59835 Da
Description	SRC: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian). This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Immunogen	Purified recombinant fragment of SRC (aa10-193) expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.

Additional Information
Other Names	Proto-oncogene tyrosine-protein kinase Src, 2.7.10.2, Proto-oncogene c-Src, pp60c-src, p60-Src, SRC, SRC1
Dilution	WB~~1/500 - 1/2000 E~~N/A
Storage	Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions	SRC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.