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FABP4 Antibody

Purified Mouse Monoclonal Antibody

     
  • 1 - FABP4 Antibody AO1202a
    Figure 1: Western blot analysis using FABP4 mouse mAb against truncated Trx-FABP4 recombinant protein (1).
  • 2 - FABP4 Antibody AO1202a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human cerebra (left) and breast carcinoma tissue (right),showing cytoplasmic and membrane location with DAB staining using ERBB3 mouse mAb.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P15090
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 5H11A4E11
Isotype IgG1
Calculated MW 14719 Da
Description FABP4: fatty acid binding protein 4, adipocyte. FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.
Immunogen Purified recombinant fragment of FABP4 (aa61-121) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 2167
Other Names Fatty acid-binding protein, adipocyte, Adipocyte lipid-binding protein, ALBP, Adipocyte-type fatty acid-binding protein, A-FABP, AFABP, Fatty acid-binding protein 4, FABP4
Dilution WB~~1/500 - 1/2000
E~~N/A
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFABP4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FABP4
Function Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P04117}. Nucleus {ECO:0000250|UniProtKB:P04117}. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export. {ECO:0000250|UniProtKB:P04117}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

1. J Biol Chem. 2004 Dec 10;279(50):52399-405. 2. Mol Cell Proteomics. 2005 Apr;4(4):570-81.

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