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BCL9L

Purified Mouse Monoclonal Antibody

     
  • 10 - BCL9L AO2626a
    Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
  • 1 - BCL9L AO2626a
    Figure 2:Western blot analysis using BCL9L mAb against human BCL9L (AA: 606-751) recombinant protein. (Expected MW is 41.9 kDa)
  • 1 - BCL9L AO2626a
    Figure 3:Western blot analysis using BCL9L mAb against HEK293 (1) and BCL9L (AA: 606-751)-hIgGFc transfected HEK293 (2) cell lysate.
  • 51 - BCL9L AO2626a
    Figure 4:Flow cytometric analysis of Hela cells using BCL9L mouse mAb (green) and negative control (red).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, ICC, E
Primary Accession Q86UU0
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1C9G2
Isotype Mouse IgG1
Calculated MW 157129 Da
Immunogen Purified recombinant fragment of human BCL9L (AA: 606-751) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 283149
Other Names BCL9-2; DLNB11
Dilution WB~~ 1/500 - 1/2000
IHC~~1:100~500
ICC~~N/A
E~~ 1/10000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBCL9L is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCL9L
Synonyms DLNB11
Function Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity).
Cellular Location Nucleus
Tissue Location Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

1.Oncotarget. 2014 Aug 30;5(16):6770-87.2.Gastroenterology. 2011 Oct;141(4):1359-70, 1370.e1-3.

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