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LAP3 Recombinant Rabbit mAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P28838 |
| Other Accession | P28838 |
| Host | Rabbit |
| Clonality | Recombinant |
| Calculated MW | 56166 Da |
| Physical State | Liquid |
| Immunogen | A synthesized peptide derived from human LAP3 |
| Epitope Specificity | 11-74 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| SIMILARITY | Belongs to the peptidase M17 family. |
| SUBUNIT | Homohexamer. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. |
| Gene ID | 51056 |
|---|---|
| Other Names | HEL-S-106; LAP; LAPEP; PEPS; 2410015L10Rik; LAP-3; Pep-7; Pep-S; Pep7; AMPL_HUMAN; LAP3; Cysteinylglycine-S-conjugate dipeptidase; Leucine aminopeptidase 3 (LAP-3); Leucyl aminopeptidase; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase; 3.4.11.1; AMPL_MOUSE; AMPL_RAT; Leucyl aminopeptidase (LAP); leucine aminopeptidase 3 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | LAP3 (HGNC:18449) |
|---|---|
| Function | Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S- conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q68FS4}. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP100056
