癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SART1 Recombinant Rabbit mAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | O43290 |
| Other Accession | O43290 |
| Reactivity | Human, Mouse |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Recombinant |
| Calculated MW | 90255 Da |
| Physical State | Liquid |
| Immunogen | A synthesized peptide derived from human SART1 |
| Epitope Specificity | 660-735/800 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| SIMILARITY | Belongs to the SNU66/SART1 family. |
| SUBUNIT | Identified in the spliceosome C complex. Part of a tri-snRNP complex. |
| Post-translational modifications | Sumoylated with SUMO2. Phosphorylated upon DNA damage, probably by ATM or ATR. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA. |
| Gene ID | 9092 |
|---|---|
| Other Names | SNUT1_HUMAN; SART1; SNU66 homolog (hSnu66); Squamous cell carcinoma antigen recognized by T-cells 1 (SART-1 | hSART-1); U4/U6.U5 tri-snRNP-associated 110 kDa protein; Ara1; HAF; HOMS1; SART1259; SNRNP110; Snu66; spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP; squamous cell carcinoma antigen recognised by T cells; squamous cell carcinoma antigen recognized by T cells 1; squamous cell carcinoma antigen recognized by T-cells 1; SART1, U4/U6.U5 tri-snRNP-associated protein 1; small nuclear ribonucleoprotein 110kDa (U4/U6.U5); hypoxia associated factor |
| Dilution | WB=1:500-2000,ICC/IF=1:50-200,Flow-Cyt=1:50-100 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SART1 |
|---|---|
| Function | Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA. |
| Cellular Location | Nucleus. Note=Found in the nucleus of mitogen- activated peripheral blood mononuclear cells (PBMCs), tumor cells, or normal cell lines, but not in normal tissues except testis and fetal liver or in unstimulated PBMCs, suggesting preferential expression in proliferating cells |
| Tissue Location | Ubiquitously expressed. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,400.00
Cat# AP100059
