Human CG beta Mouse mAb
- 产品详情
- 实验流程
Application
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P0DN86 |
| Other Accession | P0DN86 |
| Host | Mouse |
| Clonality | Monoclonal |
| Calculated MW | 17739 Da |
| Physical State | Liquid |
| Immunogen | Recombinant human Choriogonadotropin subunit beta 3 protein |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the glycoprotein hormones subunit alpha family. |
| SUBUNIT | Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008] |
| Gene ID | 1082;93659;94115 |
|---|---|
| Other Names | CGB; CGB5; CGB7; CGB8; LHB; hCGB; CGB3_HUMAN; CGB3; Choriogonadotropin subunit beta (CG-beta); Chorionic gonadotropin chain beta; chorionic gonadotropin subunit beta 3; chorionic gonadotropin, beta polypeptide; chorionic gonadotropin beta subunit 3 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CGB3 |
|---|---|
| Synonyms | CGB |
| Function | Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. |
| Cellular Location | Secreted. |
| Tissue Location | High expression in the placenta throughout pregnancy. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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