癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
LYPD3 Recombinant Rabbit mAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF, IP |
|---|---|
| Primary Accession | O95274 |
| Other Accession | O95274 |
| Host | Rabbit |
| Clonality | Recombinant |
| Calculated MW | 35971 Da |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 2 UPAR/Ly6 domains. |
| SUBUNIT | Binds laminin-1 and laminin-5. Interacts with LGALS3 By similarity. Interacts with AGR2 and AGR3. |
| Post-translational modifications | N-glycosylated and O-glycosylated. |
| Background Descriptions | Predicted to enable laminin binding activity. Involved in negative regulation of smooth muscle cell apoptotic process. Located in extracellular space. [provided by Alliance of Genome Resources, Feb 2025] |
| Gene ID | 27076 |
|---|---|
| Other Names | C4.4A; LYPD3_HUMAN; LYPD3; GPI-anchored metastasis-associated protein C4.4A homolog; Matrigel-induced gene C4 protein (MIG-C4); LY6/PLAUR domain containing 3; Ly6/PLAUR domain-containing protein 3; Matrigel-induced gene C4 protein; MIG-C4; UNQ491/PRO1007 |
| Dilution | WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,IP=1:50-200,IF=1:50-200 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | LYPD3 |
|---|---|
| Synonyms | C4.4A |
| Function | Supports cell migration. May be involved in urothelial cell- matrix interactions. May be involved in tumor progression. |
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
| Tissue Location | Expressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP100080
