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CSHL1 Recombinant Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IHC-F, IF
Primary Accession Q14406
Other Accession Q14406
Host Rabbit
Clonality Recombinant
Calculated MW 25391 Da
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY Belongs to the somatotropin/prolactin family.
Background Descriptions The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Additional Information
Gene ID 1444
Other Names CS-5; CSHP1; CSL; GHB4; hCS-L; CSHL_HUMAN; CSHL1; Chorionic somatomammotropin-like; Lactogen-like; chorionic somatomammotropin hormone like 1; chorionic somatomammotropin CS-5; Chorionic somatomammotropin hormone-like 1
Dilution WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name CSHL1
Synonyms CSHP1, CSL
Function May be a novel gestational hormone required to compensate for absence of other members of the GH/CS cluster during gestation.
Cellular Location Secreted.
Research Areas
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