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为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
STARD4 Recombinant Rabbit mAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q96DR4 |
| Other Accession | Q96DR4 |
| Host | Rabbit |
| Clonality | Recombinant |
| Calculated MW | 23517 Da |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Background Descriptions | Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008] |
| Gene ID | 134429 |
|---|---|
| Other Names | StAR related lipid transfer domain containing 4; START domain containing 4, sterol regulated; StAR-related lipid transfer protein 4; START domain-containing protein 4; StARD4 |
| Dilution | WB=1:500-2000,ICC/IF=1:50-200 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | STARD4 (HGNC:18058) |
|---|---|
| Function | Involved in the intracellular transport of cholesterol. Binds cholesterol or other sterols. |
| Cellular Location | Cytoplasm. Endoplasmic reticulum |
| Tissue Location | Expressed by macrophages and Kupffer cells. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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